API Obeticholic acid CAS 459789-99-2 for biliary cholangitis

Short Description:

Obeticholic acid is used alone or in combination treatment for a certain liver disease (primary biliary cholangitis-PBC).

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Product Detail

Product Tags

Description

Obeticholic acid is used alone or in combination treatment for a certain liver disease (primary biliary cholangitis-PBC).

Specification:

Product Name	Obeticholic Acid
Chemical Name	6-Ethylchenodeoxycholic acid
Other Name	3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-24-OIC ACID;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph;Obeticholic Acid(INT 747,6-ECDCA)
CAS Number	459789-99-2
Molecular Formula	C26H44O4
Formula Weight	420.63
Appearance	White powder
Assay	99.0% min
Density	1.091 g/cm3
Melting Point	108-110 °C
Boiling Point	562.9±25.0 °C
Package	20kg/bag/drum, 25kg/bag/drum, or as you required
Storage	Store the container tightly closed in a dry & cool place. Do not expose to direct sunlight.
COA & MSDS	Available

Usage

Obeticholic acid is a dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis. It has a role as a farnesoid X receptor agonist and a hepatoprotective agent. It is a dihydroxy-5beta-cholanic acid, a 3alpha-hydroxy steroid and a 7alpha-hydroxy steroid. It derives from a chenodeoxycholic acid.
Obeticholic acid (OCA) is a synthetically modified bile acid and potent agonist of the farnesoid X nuclear receptor (FXR) that is used to treat liver diseases including primary biliary cholangitis.