Quinine Hydrochloride Dihydrate
CAS 6119-47-7
Purity: 99%
Related products: Quinine monohydrochloride dihydrate, Quinine (hydrochloride dihydrate)
| Common Name | Quinine Hydrochloride Dihydrate | ||
| CAS Number | 6119-47-7 | Molecular Weight | 396.908 |
| Density | N/A | Boiling Point | 633ºC at 760 mmHg |
| Molecular Formula | C20H29ClN2O4 | Melting Point | 115-116 °C (dec.)(lit.) |
| Brand | SHXLCHEM | Flash Point | 122 °C |
| Items | Specifications | Results |
| Appearance | White to off-white Powder | Complies |
| Solubility | Soluble in water, freely soluble in ethanol (96%). | Complies |
| Identification | ||
| A) TLC | The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution. | Complies |
| B) Bromine and ammonia | A green colour develops when treated with bromine water and dilute ammonia | Complies |
| C) IR Spectrum | When examined in ultraviolet light at 366 nm,an intense blue fluorescence appears which disappears almost completely on the addition of 1 ml of HCL | Complies |
| D) Characteristic of chlorides | It gives the reactions of chlorides | Complies |
| E) Test for pH | Should comply | Complies |
| Appearance of solution | Solution S is clear and not more intensely coloured than reference solution GY6 | Complies |
| pH | 6.0~6.8 | 6.40 |
| Specific optical rotation | -240° ~ -226° | Complies |
| Titration with AgNO3 | 95.0 - 105.0 % | Complies |
| Other cinchona alkaloids
Impurity C Any impurity eluted before quinine Any other impurity |
NMT 10% NMT 5%
NMT 2.5% |
5.17% 1.12%
N.A |
| Water (by Karl Fischer) | 6.0 - 10.0 % | Complies |
| Sulphates | NMT 500ppm | Complies |
| Arsenic (As) | NMT 3ppm | Complies |
| Cadmium (Cd) | NMT 1ppm | Complies |
| Mercury (Hg) | NMT 1ppm | Complies |
| Lead (Pb) | NMT 10ppm | Complies |
| Barium | Should comply | Complies |
| Loss on drying | 6%~10% | 7.11% |
| Sulphated ash | NMT 0.1% | 0.06% |
| Assay(HPLC) | 99.0 %-101.0 % on dried substance | 99.3% |
| Conclusion: the product conforms to BP2015 | ||
Sample
Available
Package
1kg/25kg per drum, or as you required.
Storage
Store the container tightly closed in a dry, cool and well-ventilated place.